p62 links the autophagy pathway and the ubiqutin–proteasome

p62 links the autophagy pathway and the ubiqutin–proteasome autophagy pathway p62 Mac- roautophagy, hereafter autophagy, is a degradation pathway that plays key roles in development, tissue homeostasis, and disease p62 ทาง เข้า สล็อต However, the exact recognition mode of degrading substrates and regulation of p62 in the autophagic pathway remain unknown Here, we present the complex

p62 ทาง เข้า สล็อต Phospho-p62 with bound Keap1 interacts with LC3 through the LIR and is degraded by the autophagy pathway Thus, the cells under

p62com สล็อต p62com สล็อต p62 com Korolchuk VI, Mansilla A, Menzies FM, Rubinsztein DC Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates Mol Cell 2009;33 Selective autophagy occurs constitutively and can also be induced in response to cellular stresses for the maintenance cellular homeostasis (